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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
CYTH2
All Species:
42.42
Human Site:
T254
Identified Species:
93.33
UniProt:
Q99418
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q99418
NP_059431.1
400
46546
T254
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Chimpanzee
Pan troglodytes
XP_001154812
703
78627
T558
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Rhesus Macaque
Macaca mulatta
XP_001111690
528
60089
T383
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Dog
Lupus familis
XP_852119
400
46542
T254
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Cat
Felis silvestris
Mouse
Mus musculus
Q9QX11
398
46269
T255
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Rat
Rattus norvegicus
P63035
400
46553
T254
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001507855
453
52296
T313
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Chicken
Gallus gallus
NP_001026276
398
46264
T255
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Frog
Xenopus laevis
NP_001086260
397
46050
T254
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Zebra Danio
Brachydanio rerio
XP_697830
402
46621
T257
E
D
D
G
N
D
L
T
H
T
F
F
N
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34512
393
45063
S237
T
E
V
Y
E
S
V
S
V
T
Q
F
K
I
P
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
48.6
75.5
99.7
N.A.
82.2
99.2
N.A.
71.9
82.7
78.5
87
N.A.
N.A.
N.A.
40
N.A.
Protein Similarity:
100
52
75.5
100
N.A.
91.5
100
N.A.
81
92
90
93.7
N.A.
N.A.
N.A.
61.2
N.A.
P-Site Identity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
100
100
N.A.
100
100
N.A.
100
100
100
100
N.A.
N.A.
N.A.
33.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
91
91
0
0
91
0
0
0
0
0
0
0
0
91
% D
% Glu:
91
10
0
0
10
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
91
100
0
0
0
% F
% Gly:
0
0
0
91
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
91
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% I
% Lys:
0
0
0
0
0
0
0
0
0
0
0
0
10
0
0
% K
% Leu:
0
0
0
0
0
0
91
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
91
0
0
0
0
0
0
0
91
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
91
10
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
10
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% S
% Thr:
10
0
0
0
0
0
0
91
0
100
0
0
0
0
0
% T
% Val:
0
0
10
0
0
0
10
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _